國立虎尾科技大學 |

G-protein-coupled receptor dimers

Record Type:	Language materials, printed : Monograph/item
Title/Author:	G-protein-coupled receptor dimers/ edited by Katharine Herrick-Davis, Graeme Milligan, Giuseppe Di Giovanni.
other author:	Herrick-Davis, Katharine.
Published:	Cham :Springer International Publishing : : 2017.,
Description:	xvii, 501 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	G proteins - Receptors. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-60174-8
ISBN:	9783319601748

G-protein-coupled receptor dimers
G-protein-coupled receptor dimers[electronic resource] /edited by Katharine Herrick-Davis, Graeme Milligan, Giuseppe Di Giovanni. - Cham :Springer International Publishing :2017. - xvii, 501 p. :ill., digital ;24 cm. - The receptors ;v.33. - Receptors ;v.28..

Part I. Introduction -- 1. From Monomers to Dimers and Beyond: An Exciting Journey in the World of the G protein-coupled Receptor Family -- 2. The use of Spatial Intensity Distribution Analysis to Examine G protein-coupled Receptor Oligomerization -- 3. Advanced Microscopy Techniques for Studying G protein-coupled Receptors -- Part II. Receptors -- 4. Light Sensing G protein-coupled Receptor Rhodopsin Dimer -- 5. Extreme Vetting of Dopamine Receptor Oligomerization -- 6. Serotonin receptors -- 7. Cannabinoid and Opioid Receptor Heteromers -- 8. Di/oligomerization of Glycoprotein Hormone Receptors -- 9. Chemokine Receptor Oligomerization to Tweak Chemotactic Responses -- 10. Secretin Receptor Dimerization. Prototypic of Class B GPCR Behavior -- 11. Receptors and RAMPs -- 12. Obligatory Heterodimerization of GABAB Receptor -- 13. Metabotropic Glutamate Receptors. Part III. Assembly and Trafficking -- 14. The monomer/homodimer Equilibrium of G protein-coupled Receptors: Formation in the Secretory Pathway and Potential Functional Significance -- 15. Probing Self-assembly of G protein-coupled Receptor Oligomers in Membranes using Molecular Dynamics Modeling and Experimental Approaches -- 16. Interaction of Membrane Cholesterol with GPCRs: Implications in Receptor Oligomerization -- Part IV. Physiology and Therapeutic Potential -- 17. Allosterism within GPCR Oligomers: Back to Symmetry -- 18. Understanding the Physiological Significance of GPCR Dimers and Oligomers -- 19. Heteromers form Novel Signaling Complexes -- 20. Heteroreceptor Complexes Implicated in Parkinson's Disease.

G-protein-coupled receptors (GPCRs) are believed to be the largest family of membrane proteins involved in signal transduction and cellular responses. They dimerize (form a pair of macromolecules) with a wide variety of other receptors. The proposed book will provide a comprehensive overview of GPCR dimers, starting with a historical perspective and including, basic information about the different dimers, how they synthesize, their signaling properties, and the many diverse physiological processes in which they are involved. In addition to presenting information about healthy GPCR dimer activity, the book will also include a section on their pathology and therapeutic potentials.

ISBN: 9783319601748

Standard No.: 10.1007/978-3-319-60174-8doiSubjects--Topical Terms:

583423
G proteins
--Receptors.

LC Class. No.: QP552.G16

Dewey Class. No.: 572.6

G-protein-coupled receptor dimers
LDR:03321nam a2200325 a 4500 001 923367
003 DE-He213
005 20180312114355.0
006 m d
007 cr nn 008maaau
008 190625s2017 gw s 0 eng d
020 $a 9783319601748 $q (electronic bk.)
020 $a 9783319601724 $q (paper)
024 7 $a 10.1007/978-3-319-60174-8 $2 doi
035 $a 978-3-319-60174-8
040 $a GP $c GP
041 0 $a eng
050 4 $a QP552.G16
072 7 $a PSAN $2 bicssc
072 7 $a MED057000 $2 bisacsh
082 0 4 $a 572.6 $2 23
090 $a QP552.G16 $b G111 2017
245 0 0 $a G-protein-coupled receptor dimers $h [electronic resource] / $c edited by Katharine Herrick-Davis, Graeme Milligan, Giuseppe Di Giovanni.
260 $a Cham : $c 2017. $b Springer International Publishing : $b Imprint: Humana Press,
300 $a xvii, 501 p. : $b ill., digital ; $c 24 cm.
490 1 $a The receptors ; $v v.33
505 0 $a Part I. Introduction -- 1. From Monomers to Dimers and Beyond: An Exciting Journey in the World of the G protein-coupled Receptor Family -- 2. The use of Spatial Intensity Distribution Analysis to Examine G protein-coupled Receptor Oligomerization -- 3. Advanced Microscopy Techniques for Studying G protein-coupled Receptors -- Part II. Receptors -- 4. Light Sensing G protein-coupled Receptor Rhodopsin Dimer -- 5. Extreme Vetting of Dopamine Receptor Oligomerization -- 6. Serotonin receptors -- 7. Cannabinoid and Opioid Receptor Heteromers -- 8. Di/oligomerization of Glycoprotein Hormone Receptors -- 9. Chemokine Receptor Oligomerization to Tweak Chemotactic Responses -- 10. Secretin Receptor Dimerization. Prototypic of Class B GPCR Behavior -- 11. Receptors and RAMPs -- 12. Obligatory Heterodimerization of GABAB Receptor -- 13. Metabotropic Glutamate Receptors. Part III. Assembly and Trafficking -- 14. The monomer/homodimer Equilibrium of G protein-coupled Receptors: Formation in the Secretory Pathway and Potential Functional Significance -- 15. Probing Self-assembly of G protein-coupled Receptor Oligomers in Membranes using Molecular Dynamics Modeling and Experimental Approaches -- 16. Interaction of Membrane Cholesterol with GPCRs: Implications in Receptor Oligomerization -- Part IV. Physiology and Therapeutic Potential -- 17. Allosterism within GPCR Oligomers: Back to Symmetry -- 18. Understanding the Physiological Significance of GPCR Dimers and Oligomers -- 19. Heteromers form Novel Signaling Complexes -- 20. Heteroreceptor Complexes Implicated in Parkinson's Disease.
520 $a G-protein-coupled receptors (GPCRs) are believed to be the largest family of membrane proteins involved in signal transduction and cellular responses. They dimerize (form a pair of macromolecules) with a wide variety of other receptors. The proposed book will provide a comprehensive overview of GPCR dimers, starting with a historical perspective and including, basic information about the different dimers, how they synthesize, their signaling properties, and the many diverse physiological processes in which they are involved. In addition to presenting information about healthy GPCR dimer activity, the book will also include a section on their pathology and therapeutic potentials.
650 0 $a G proteins $x Receptors. $3 583423
650 0 $a Dimers. $3 1199690
650 1 4 $a Biomedicine. $3 593880
650 2 4 $a Neurosciences. $3 593561
700 1 $a Herrick-Davis, Katharine. $3 1199688
700 1 $a Milligan, Graeme. $3 1199689
700 1 $a Di Giovanni, Giuseppe. $3 782717
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
830 0 $a Receptors ; $v v.28. $3 1115237
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-60174-8
950 $a Biomedical and Life Sciences (Springer-11642)