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The heterogeneity of cancer metabolism
~
SpringerLink (Online service)
The heterogeneity of cancer metabolism
Record Type:
Language materials, printed : Monograph/item
Title/Author:
The heterogeneity of cancer metabolism/ edited by Anne Le.
other author:
Le, Anne.
Published:
Cham :Springer International Publishing : : 2018.,
Description:
xv, 183 p. :ill., digital ; : 24 cm.;
Contained By:
Springer eBooks
Subject:
Cancer cells - Metabolism. -
Online resource:
http://dx.doi.org/10.1007/978-3-319-77736-8
ISBN:
9783319777368
The heterogeneity of cancer metabolism
The heterogeneity of cancer metabolism
[electronic resource] /edited by Anne Le. - Cham :Springer International Publishing :2018. - xv, 183 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.10630065-2598 ;. - Advances in experimental medicine and biology ;780..
Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
ISBN: 9783319777368
Standard No.: 10.1007/978-3-319-77736-8doiSubjects--Topical Terms:
1023916
Cancer cells
--Metabolism.
LC Class. No.: RC269.7 / .H484 2018
Dewey Class. No.: 616.99407
The heterogeneity of cancer metabolism
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Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
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Biomedical and Life Sciences (Springer-11642)
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