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Modeling methods for medical systems biology = regulatory dynamics underlying the emergence of disease processes /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Modeling methods for medical systems biology/ by Maria Elena Alvarez-Buylla Roces ... [et al.].
Reminder of title:	regulatory dynamics underlying the emergence of disease processes /
other author:	Alvarez-Buylla Roces, Maria Elena.
Published:	Cham :Springer International Publishing : : 2018.,
Description:	xxi, 258 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Biological models. -
Online resource:	http://dx.doi.org/10.1007/978-3-319-89354-9
ISBN:	9783319893549

Modeling methods for medical systems biology = regulatory dynamics underlying the emergence of disease processes /
Modeling methods for medical systems biologyregulatory dynamics underlying the emergence of disease processes /[electronic resource] :by Maria Elena Alvarez-Buylla Roces ... [et al.]. - Cham :Springer International Publishing :2018. - xxi, 258 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.10690065-2598 ;. - Advances in experimental medicine and biology ;780..

Introduction -- Medical systems biology -- Modeling procedures -- Case of study -- Conclusions and Perspectives -- Bibliography.

This book contributes to better understand how lifestyle modulations can effectively halt the emergence and progression of human diseases. The book will allow the reader to gain a better understanding of the mechanisms by which the environment interferes with the bio-molecular regulatory processes underlying the emergence and progression of complex diseases, such as cancer. Focusing on key and early cellular bio-molecular events giving rise to the emergence of degenerative chronic disease, it builds on previous experience on the development of multi-cellular organisms, to propose a mathematical and computer based framework that allows the reader to analyze the complex interplay between bio-molecular processes and the (micro)-environment from an integrative, mechanistic, quantitative and dynamical perspective. Taking the wealth of empirical evidence that exists it will show how to build and analyze models of core regulatory networks involved in the emergence and progression of chronic degenerative diseases, using a bottom-up approach.

ISBN: 9783319893549

Standard No.: 10.1007/978-3-319-89354-9doiSubjects--Topical Terms:

560717
Biological models.

LC Class. No.: QH324.8

Dewey Class. No.: 570.1

Modeling methods for medical systems biology = regulatory dynamics underlying the emergence of disease processes /
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