國立虎尾科技大學 |

Molecular and cell biology of cancer = when cells break the rules and hijack their own planet /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Molecular and cell biology of cancer/ edited by Rita Fior, Rita Zilhao.
Reminder of title:	when cells break the rules and hijack their own planet /
other author:	Fior, Rita.
Published:	Cham :Springer International Publishing : : 2019.,
Description:	ix, 216 p. :ill., digital ; : 24 cm.;
Contained By:	Springer eBooks
Subject:	Cancer - Molecular aspects. -
Online resource:	https://doi.org/10.1007/978-3-030-11812-9
ISBN:	9783030118129

Molecular and cell biology of cancer = when cells break the rules and hijack their own planet /
Molecular and cell biology of cancerwhen cells break the rules and hijack their own planet /[electronic resource] :edited by Rita Fior, Rita Zilhao. - Cham :Springer International Publishing :2019. - ix, 216 p. :ill., digital ;24 cm. - Learning materials in biosciences,2509-6125. - Learning materials in biosciences..

Preface -- Molecular and Cell Biology of Cancer when cells break the rules and hijack their own planet -- Cancer as an Evolutionary Process -- Cell signaling in cancer -- The cell cycle, cytoskeleton and cancer -- Genomic Instability: DNA Repair and Cancer -- Cell metabolism in cancer - an energetic switch -- Cancer immunoediting and hijacking of the immune system -- Angiogenesis - vessels recruitment by tumor cells -- Tumor niche disruption and metastasis: the role of epithelial-mesenchymal transition (EMT) -- Case studies - Molecular Pathology perspective and impact on oncologic patients' management -- Index.

This textbook takes you on a journey to the basic concepts of cancer biology. It combines developmental, evolutionary and cell biology perspectives, to then wrap-up with an integrated clinical approach. The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent chapters are detailed and the idea of cancer as a mass of somatic cells undergoing a micro-evolutionary Darwinian process is explored. Further, the main Hanahan and Weinberg "Hallmarks of Cancer" are revisited. In most chapters, the fundamental experiments that led to key concepts, connecting basic biology and biomedicine are highlighted. In the book's closing section all of these concepts are integrated in clinical studies, where molecular diagnosis as well as the various classical and modern therapeutic strategies are addressed. The book is written in an easy-to-read language, like a one-on-one conversation between the writer and the reader, without compromising the scientific accuracy. Therefore, this book is suited not only for advanced undergraduates and master students but also for patients or curious lay people looking for a further understanding of this shattering disease.

ISBN: 9783030118129

Standard No.: 10.1007/978-3-030-11812-9doiSubjects--Topical Terms:

668357
Cancer
--Molecular aspects.

LC Class. No.: RC268.4 / .M65 2019

Dewey Class. No.: 616.9940421

Molecular and cell biology of cancer = when cells break the rules and hijack their own planet /
LDR:02905nam a2200337 a 4500 001 940934
003 DE-He213
005 20190627061223.0
006 m d
007 cr nn 008maaau
008 200417s2019 gw s 0 eng d
020 $a 9783030118129 $q (electronic bk.)
020 $a 9783030118112 $q (paper)
024 7 $a 10.1007/978-3-030-11812-9 $2 doi
035 $a 978-3-030-11812-9
040 $a GP $c GP
041 0 $a eng
050 4 $a RC268.4 $b .M65 2019
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
072 7 $a MJCL $2 thema
082 0 4 $a 616.9940421 $2 23
090 $a RC268.4 $b .M718 2019
245 0 0 $a Molecular and cell biology of cancer $h [electronic resource] : $b when cells break the rules and hijack their own planet / $c edited by Rita Fior, Rita Zilhao.
260 $a Cham : $c 2019. $b Springer International Publishing : $b Imprint: Springer,
300 $a ix, 216 p. : $b ill., digital ; $c 24 cm.
490 1 $a Learning materials in biosciences, $x 2509-6125
505 0 $a Preface -- Molecular and Cell Biology of Cancer when cells break the rules and hijack their own planet -- Cancer as an Evolutionary Process -- Cell signaling in cancer -- The cell cycle, cytoskeleton and cancer -- Genomic Instability: DNA Repair and Cancer -- Cell metabolism in cancer - an energetic switch -- Cancer immunoediting and hijacking of the immune system -- Angiogenesis - vessels recruitment by tumor cells -- Tumor niche disruption and metastasis: the role of epithelial-mesenchymal transition (EMT) -- Case studies - Molecular Pathology perspective and impact on oncologic patients' management -- Index.
520 $a This textbook takes you on a journey to the basic concepts of cancer biology. It combines developmental, evolutionary and cell biology perspectives, to then wrap-up with an integrated clinical approach. The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent chapters are detailed and the idea of cancer as a mass of somatic cells undergoing a micro-evolutionary Darwinian process is explored. Further, the main Hanahan and Weinberg "Hallmarks of Cancer" are revisited. In most chapters, the fundamental experiments that led to key concepts, connecting basic biology and biomedicine are highlighted. In the book's closing section all of these concepts are integrated in clinical studies, where molecular diagnosis as well as the various classical and modern therapeutic strategies are addressed. The book is written in an easy-to-read language, like a one-on-one conversation between the writer and the reader, without compromising the scientific accuracy. Therefore, this book is suited not only for advanced undergraduates and master students but also for patients or curious lay people looking for a further understanding of this shattering disease.
650 0 $a Cancer $x Molecular aspects. $3 668357
650 1 4 $a Cancer Research. $3 668358
650 2 4 $a Human Genetics. $3 593893
650 2 4 $a Molecular Medicine. $3 668353
650 2 4 $a Cell Biology. $3 593889
650 2 4 $a Metabolomics. $3 882386
700 1 $a Fior, Rita. $3 1227901
700 1 $a Zilhao, Rita. $3 1227902
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer eBooks
830 0 $a Learning materials in biosciences. $3 1113322
856 4 0 $u https://doi.org/10.1007/978-3-030-11812-9
950 $a Biomedical and Life Sciences (Springer-11642)