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Endogenous ADP-Ribosylation

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Endogenous ADP-Ribosylation/ edited by Friedrich Koch-Nolte.
other author:	Koch-Nolte, Friedrich.
Description:	VIII, 213 p.online resource. :
Contained By:	Springer Nature eBook
Subject:	Pharmacology. -
Online resource:	https://doi.org/10.1007/978-3-319-10771-4
ISBN:	9783319107714

Endogenous ADP-Ribosylation
Endogenous ADP-Ribosylation[electronic resource] /edited by Friedrich Koch-Nolte. - 1st ed. 2015. - VIII, 213 p.online resource. - Current Topics in Microbiology and Immunology,3840070-217X ;. - Current Topics in Microbiology and Immunology,387.

The natural history of ADP-ribosyltransferases and the ADP ribosylation system -- Identification and Analysis of ADP-ribosylated Proteins -- Photorhabdus luminescens toxins TccC3 and TccC5: Insecticidal ADP-ribosyltransferases that modify threonine and glutamine -- Reaction mechanism of mono-ADP-ribosyltransferase based on structures of the complex of enzyme and substrate protein -- Regulation of nitrogenase by reversible mono-ADP-ribosylation -- ADP-ribosylation of P2X7: a matter of life and death for regulatory T cells and natural killer T cells -- Pierisins and CARP-1: ADP-ribosylation of DNA by ARTCs in butterflies and shellfish -- Comparative structural analysis of the putative mono-ADP-ribosyltransferases of the ARTD/PARP family -- Function and regulation of the mono-ADP-ribosyltransferase ARTD10 -- Regulation of nucleocytoplasmic transport by ADP-ribosylation: the emerging role of karyopherin-β1 mono-ADP-ribosylation by ARTD15.

This volume gathers the latest exciting findings on ADP-ribosylation from renowned experts in the field. It includes ten chapters, organized into the following three thematic sections: · Evolution and detection of endogenous ADP-ribosylation · ADP-ribosylation by the ARTC family of ADP-ribosyltransferases (R-S-E ARTs) · ADP-ribosylation by the ARTD family of ADP-ribosyltransferases (H-Y-E ARTs) The book will provide readers a better understanding of ADP-ribosylating toxins and their endogenous relatives. This provides a basis for developing novel toxin-neutralizing drugs and drugs targeting endogenous ADP-ribosyltransferase relatives.

ISBN: 9783319107714

Standard No.: 10.1007/978-3-319-10771-4doiSubjects--Topical Terms:

583819
Pharmacology.

LC Class. No.: RM1-950

Dewey Class. No.: 615

Endogenous ADP-Ribosylation
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