國立虎尾科技大學 |

RNA/DNA and Cancer

Record Type:	Language materials, printed : Monograph/item
Title/Author:	RNA/DNA and Cancer/ by Joseph G. Sinkovics.
Author:	Sinkovics, Joseph G.
Description:	XI, 815 p. 75 illus., 52 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Cancer research. -
Online resource:	https://doi.org/10.1007/978-3-319-22279-0
ISBN:	9783319222790

RNA/DNA and Cancer
Sinkovics, Joseph G.

RNA/DNA and Cancer[electronic resource] /by Joseph G. Sinkovics. - 1st ed. 2016. - XI, 815 p. 75 illus., 52 illus. in color.online resource.

Preface. Introductions. I THE PRIMORDIAL RNA/DNA COMPLEX EVOLVING -- The Primordial Genes Are Conserved as Stem Cell Genes and Proto-Oncogenes -- The First Cells Ascend -- Eukaryotic Single Cells and the First Cell Communities Then and Now -- A Highly Effective Immune System Predating Adaptive Immunity -- Elements of Adaptive Immunity Self-Assemble -- The RNA/DNA Complex at Work -- YY Proteins -- Elusive Alleles -- The Long Trajectory of the IGF-like Receptor and Its Ligands -- Primordial Fused Genes Become Oncogenes and Encode Oncoproteins -- Performance in the Laboratory -- Inbuilt Errors not yet Corrected -- Errors or Inherent Attributes for the Sustenance of Unicellular Life -- Viral Genomic Insertions into the Host Cell’s Genome -- Viral and Cellular Proteins Interact -- Light Cast to Broken DNA, Its Repair, and Consequences -- Undisciplined Introns -- Elementary Epigenomics -- RNA/DNA: Bioengineers Supreme -- II THE ONCOGENOME -- Seamless Unity of the Nucleus and Cytoplasm: the Membranes Are Permeable -- Endogenously Initiated Immortalization is Welcome. Enforced Carcinogenesis by Exogenous Alien Initiator Is Resisted -- A Condensed Compendium -- “Malignant Transformation” -- III THE HUMAN CEREBRAL CORTICAL DNA AGAINST CANCER CELL DNA -- Will the Human Cerebral Cortex Subdue the Oncogenome?- In Self-Defense, the Cancer Cell Reactivates Its Primordial Genome Loaded with Proviruses in Order to Mobilize All Its Remaining Survival Pathways -- The Cancer Cell Viewed as a Unicellular Parasite (an Amoeba) -- Astute Observers Withstand Derision -- “Making Cancer History” at M.D. Anderson Hospital -- SUMMARY -- Appendix 1 -- Appendix 2 -- Index. .

In this book, the author Joseph G. Sinkovics liberally shares his views on the cancer cell which he has been observing in vivo and in vitro, over a life time. Readers will learn how, as an inherent faculty of the RNA/DNA complex, the primordial cell survival pathways are endogenously reactivated in an amplified or constitutive manner in the multicellular host, and are either masquerading as self-elements or as placentas, to which the multicellular host is evolutionarily trained to extend full support. The host obliges. The author explains that there is no such evidence that “malignantly transformed” human cells survive in nature. However, when cared for in the laboratory, these cells live and replicate as immortalized cultures. These cells retain their vitality upon storage in liquid nitrogen. One can only imagine an astrophysical environment in which such cells could survive; perhaps, first their seemingly humble exosomes would populate that environment. Immortal cell populations so created may survive as individuals, or may even re-organize themselves into multicellular colonies, as representatives of life for the duration of the Universe. This thought-provoking book is the work of a disciplined investigator and clinician with an impeccable reputation, and he enters a territory that very few if any before him have approached from the same angles. It will appeal to researchers with an interest in cell survival pathways and those researching cancer cells. .

ISBN: 9783319222790

Standard No.: 10.1007/978-3-319-22279-0doiSubjects--Topical Terms:

1253664
Cancer research.

LC Class. No.: RC261-271

Dewey Class. No.: 614.5999

RNA/DNA and Cancer
LDR:04505nam a22003975i 4500 001 974850
003 DE-He213
005 20200702162357.0
007 cr nn 008mamaa
008 201211s2016 gw | s |||| 0|eng d
020 $a 9783319222790 $9 978-3-319-22279-0
024 7 $a 10.1007/978-3-319-22279-0 $2 doi
035 $a 978-3-319-22279-0
050 4 $a RC261-271
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
072 7 $a MJCL $2 thema
082 0 4 $a 614.5999 $2 23
100 1 $a Sinkovics, Joseph G. $4 aut $4 http://id.loc.gov/vocabulary/relators/aut $3 1107399
245 1 0 $a RNA/DNA and Cancer $h [electronic resource] / $c by Joseph G. Sinkovics.
250 $a 1st ed. 2016.
264 1 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2016.
300 $a XI, 815 p. 75 illus., 52 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
505 0 $a Preface. Introductions. I THE PRIMORDIAL RNA/DNA COMPLEX EVOLVING -- The Primordial Genes Are Conserved as Stem Cell Genes and Proto-Oncogenes -- The First Cells Ascend -- Eukaryotic Single Cells and the First Cell Communities Then and Now -- A Highly Effective Immune System Predating Adaptive Immunity -- Elements of Adaptive Immunity Self-Assemble -- The RNA/DNA Complex at Work -- YY Proteins -- Elusive Alleles -- The Long Trajectory of the IGF-like Receptor and Its Ligands -- Primordial Fused Genes Become Oncogenes and Encode Oncoproteins -- Performance in the Laboratory -- Inbuilt Errors not yet Corrected -- Errors or Inherent Attributes for the Sustenance of Unicellular Life -- Viral Genomic Insertions into the Host Cell’s Genome -- Viral and Cellular Proteins Interact -- Light Cast to Broken DNA, Its Repair, and Consequences -- Undisciplined Introns -- Elementary Epigenomics -- RNA/DNA: Bioengineers Supreme -- II THE ONCOGENOME -- Seamless Unity of the Nucleus and Cytoplasm: the Membranes Are Permeable -- Endogenously Initiated Immortalization is Welcome. Enforced Carcinogenesis by Exogenous Alien Initiator Is Resisted -- A Condensed Compendium -- “Malignant Transformation” -- III THE HUMAN CEREBRAL CORTICAL DNA AGAINST CANCER CELL DNA -- Will the Human Cerebral Cortex Subdue the Oncogenome?- In Self-Defense, the Cancer Cell Reactivates Its Primordial Genome Loaded with Proviruses in Order to Mobilize All Its Remaining Survival Pathways -- The Cancer Cell Viewed as a Unicellular Parasite (an Amoeba) -- Astute Observers Withstand Derision -- “Making Cancer History” at M.D. Anderson Hospital -- SUMMARY -- Appendix 1 -- Appendix 2 -- Index. .
520 $a In this book, the author Joseph G. Sinkovics liberally shares his views on the cancer cell which he has been observing in vivo and in vitro, over a life time. Readers will learn how, as an inherent faculty of the RNA/DNA complex, the primordial cell survival pathways are endogenously reactivated in an amplified or constitutive manner in the multicellular host, and are either masquerading as self-elements or as placentas, to which the multicellular host is evolutionarily trained to extend full support. The host obliges. The author explains that there is no such evidence that “malignantly transformed” human cells survive in nature. However, when cared for in the laboratory, these cells live and replicate as immortalized cultures. These cells retain their vitality upon storage in liquid nitrogen. One can only imagine an astrophysical environment in which such cells could survive; perhaps, first their seemingly humble exosomes would populate that environment. Immortal cell populations so created may survive as individuals, or may even re-organize themselves into multicellular colonies, as representatives of life for the duration of the Universe. This thought-provoking book is the work of a disciplined investigator and clinician with an impeccable reputation, and he enters a territory that very few if any before him have approached from the same angles. It will appeal to researchers with an interest in cell survival pathways and those researching cancer cells. .
650 0 $a Cancer research. $3 1253664
650 0 $a Cell biology. $3 1253486
650 0 $a Immunology. $3 592892
650 0 $a Oncology . $3 1253469
650 1 4 $a Cancer Research. $3 668358
650 2 4 $a Cell Biology. $3 593889
650 2 4 $a Oncology. $3 593951
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9783319222783
776 0 8 $i Printed edition: $z 9783319222806
776 0 8 $i Printed edition: $z 9783319793870
856 4 0 $u https://doi.org/10.1007/978-3-319-22279-0
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)