國立虎尾科技大學 |

Clinical Trials of Antidepressants = How Changing the Model Can Uncover New, More Effective Molecules /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Clinical Trials of Antidepressants/ by Martin M. Katz.
Reminder of title:	How Changing the Model Can Uncover New, More Effective Molecules /
Author:	Katz, Martin M.
Description:	XV, 66 p. 3 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Health psychology. -
Online resource:	https://doi.org/10.1007/978-3-319-26464-6
ISBN:	9783319264646

Clinical Trials of Antidepressants = How Changing the Model Can Uncover New, More Effective Molecules /
Katz, Martin M.

Clinical Trials of AntidepressantsHow Changing the Model Can Uncover New, More Effective Molecules /[electronic resource] :by Martin M. Katz. - 1st ed. 2016. - XV, 66 p. 3 illus. in color.online resource. - SpringerBriefs in Psychology,2192-8363. - SpringerBriefs in Psychology,.

Introduction -- Why Now the Need for a New Clinical Trial Model for Antidepressants? -- Reconceptualizing Depression and the Componential-Specific Model of Clinical Trials -- Aims and Basic requirements of Clinical Trials: Conventional and Component-Specific Models -- Methods for Measuring the Components and Profile of Drug Actions: The Multivantaged Approach -- The Component-Specific Model Applied in a Clinical Trial: An Example -- Comparing the Component-Specific Model Directly with the Established Diagnosis-Specific Trial -- Prediction and Shortening the Clinical Trial: Further Advantages of the Component-Specific Model -- The Video Clinical Trial and the VIBES Method -- Conclusions.

This brief guide takes current clinical trial protocols to task and replaces them with a contemporary framework for improving next-generation antidepressants and their underlying science. Innovative models are based on a nuanced, neurologically-informed understanding of drug mechanisms and the component cognitive, mood, and behavioral aspects of depression. The book reconceptualizes not only the clinical trial process but the clinical concept of depression itself as essential to bringing pharmaceutical research and development up to date, boosting efficiency and effectiveness, finding new molecules, and reducing waste. Case studies and a review of salient depression scales illustrate the potential benefits of such wide-scale change. Included in the coverage: Why now the need for a new clinical trials model for antidepressants? Aims and basic requirements of clinical trials: conventional and component-specific models. Methods for measuring the components and the profile of drug actions: the multivantaged approach. Achieving the ideal clinical trial: an example of the merged componential and established models. Prediction and shortening the clinical trial. The video clinical trial. Clinical Trials of Antidepressants will interest a varied audience, including clinical investigators, academic and pharmaceutical company scientists, clinical trial organizations, psychiatrists, outpatient physicians, psychotherapists, clinical psychologists, psychology graduate students, medical students, and government agencies such as the FDA.

ISBN: 9783319264646

Standard No.: 10.1007/978-3-319-26464-6doiSubjects--Topical Terms:

1109770
Health psychology.

LC Class. No.: R726.7

Dewey Class. No.: 616.89

Clinical Trials of Antidepressants = How Changing the Model Can Uncover New, More Effective Molecules /
LDR:03663nam a22003975i 4500 001 977808
003 DE-He213
005 20200705042227.0
007 cr nn 008mamaa
008 201211s2016 gw | s |||| 0|eng d
020 $a 9783319264646 $9 978-3-319-26464-6
024 7 $a 10.1007/978-3-319-26464-6 $2 doi
035 $a 978-3-319-26464-6
050 4 $a R726.7
072 7 $a MBNH9 $2 bicssc
072 7 $a PSY003000 $2 bisacsh
072 7 $a MBNH9 $2 thema
082 0 4 $a 616.89 $2 23
100 1 $a Katz, Martin M. $4 aut $4 http://id.loc.gov/vocabulary/relators/aut $3 1076838
245 1 0 $a Clinical Trials of Antidepressants $h [electronic resource] : $b How Changing the Model Can Uncover New, More Effective Molecules / $c by Martin M. Katz.
250 $a 1st ed. 2016.
264 1 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2016.
300 $a XV, 66 p. 3 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
490 1 $a SpringerBriefs in Psychology, $x 2192-8363
505 0 $a Introduction -- Why Now the Need for a New Clinical Trial Model for Antidepressants? -- Reconceptualizing Depression and the Componential-Specific Model of Clinical Trials -- Aims and Basic requirements of Clinical Trials: Conventional and Component-Specific Models -- Methods for Measuring the Components and Profile of Drug Actions: The Multivantaged Approach -- The Component-Specific Model Applied in a Clinical Trial: An Example -- Comparing the Component-Specific Model Directly with the Established Diagnosis-Specific Trial -- Prediction and Shortening the Clinical Trial: Further Advantages of the Component-Specific Model -- The Video Clinical Trial and the VIBES Method -- Conclusions.
520 $a This brief guide takes current clinical trial protocols to task and replaces them with a contemporary framework for improving next-generation antidepressants and their underlying science. Innovative models are based on a nuanced, neurologically-informed understanding of drug mechanisms and the component cognitive, mood, and behavioral aspects of depression. The book reconceptualizes not only the clinical trial process but the clinical concept of depression itself as essential to bringing pharmaceutical research and development up to date, boosting efficiency and effectiveness, finding new molecules, and reducing waste. Case studies and a review of salient depression scales illustrate the potential benefits of such wide-scale change. Included in the coverage: Why now the need for a new clinical trials model for antidepressants? Aims and basic requirements of clinical trials: conventional and component-specific models. Methods for measuring the components and the profile of drug actions: the multivantaged approach. Achieving the ideal clinical trial: an example of the merged componential and established models. Prediction and shortening the clinical trial. The video clinical trial. Clinical Trials of Antidepressants will interest a varied audience, including clinical investigators, academic and pharmaceutical company scientists, clinical trial organizations, psychiatrists, outpatient physicians, psychotherapists, clinical psychologists, psychology graduate students, medical students, and government agencies such as the FDA.
650 0 $a Health psychology. $3 1109770
650 1 4 $a Health Psychology. $3 668198
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9783319264639
776 0 8 $i Printed edition: $z 9783319264653
830 0 $a SpringerBriefs in Psychology, $x 2192-8363 $3 1257642
856 4 0 $u https://doi.org/10.1007/978-3-319-26464-6
912 $a ZDB-2-BSP
912 $a ZDB-2-SXBP
950 $a Behavioral Science and Psychology (SpringerNature-41168)
950 $a Behavioral Science and Psychology (R0) (SpringerNature-43718)