國立虎尾科技大學 |

Nuclear-Cytoplasmic Transport

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Nuclear-Cytoplasmic Transport/ edited by Weidong Yang.
other author:	Yang, Weidong.
Description:	VI, 274 p. 44 illus., 40 illus. in color.online resource. :
Contained By:	Springer Nature eBook
Subject:	Nucleic acids. -
Online resource:	https://doi.org/10.1007/978-3-319-77309-4
ISBN:	9783319773094

Nuclear-Cytoplasmic Transport
Nuclear-Cytoplasmic Transport[electronic resource] /edited by Weidong Yang. - 1st ed. 2018. - VI, 274 p. 44 illus., 40 illus. in color.online resource. - Nucleic Acids and Molecular Biology,330933-1891 ;. - Nucleic Acids and Molecular Biology,31.

Assembly of the nuclear pore complex -- Structure of Yeast nuclear pore complexes -- Structure and function of nucleoporins in nuclear transport -- Dynamic structures of the nuclear pore complex and their roles in nucleo-cytoplasmic transport -- Non-canonical roles of nuclear pore proteins -- On the role of the channel nucleoporins in nuclear transport -- Structures of Importins and Exportins -- Navigating the Nuclear Envelope: one or multiple transport mechanisms for integral membrane proteins? -- mRNA export and its dysregulation in disease -- Coarse-grained molecular dynamics of the natively-unfolded domain of the NPC -- On the effects of leukemogenic nucleoporin fusion proteins on nucleocytoplasmic transport and gene expression -- Structure and Function of the Nuclear Pore Complex Revealed by Advanced Fluorescence Microscopy.

Dysfunction of nuclear-cytoplasmic transport systems has been associated with many human diseases. Thus, understanding of how functional this transport system maintains, or through dysfunction fails to maintain remains the core question in cell biology. In eukaryotic cells, the nuclear envelope (NE) separates the genetic transcription in the nucleus from the translational machinery in the cytoplasm. Thousands of nuclear pore complexes (NPCs) embedded on the NE selectively mediate the bidirectional trafficking of macromolecules such as RNAs and proteins between these two cellular compartments. In this book, the authors integrate recent progress on the structure of NPC and the mechanism of nuclear-cytoplasmic transport system in vitro and in vivo.

ISBN: 9783319773094

Standard No.: 10.1007/978-3-319-77309-4doiSubjects--Topical Terms:

788506
Nucleic acids.

LC Class. No.: QD433-436

Dewey Class. No.: 572.84

Nuclear-Cytoplasmic Transport
LDR:03011nam a22004095i 4500 001 987671
003 DE-He213
005 20200630103007.0
007 cr nn 008mamaa
008 201225s2018 gw | s |||| 0|eng d
020 $a 9783319773094 $9 978-3-319-77309-4
024 7 $a 10.1007/978-3-319-77309-4 $2 doi
035 $a 978-3-319-77309-4
050 4 $a QD433-436
072 7 $a PSB $2 bicssc
072 7 $a SCI007000 $2 bisacsh
072 7 $a PSB $2 thema
082 0 4 $a 572.84 $2 23
245 1 0 $a Nuclear-Cytoplasmic Transport $h [electronic resource] / $c edited by Weidong Yang.
250 $a 1st ed. 2018.
264 1 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2018.
300 $a VI, 274 p. 44 illus., 40 illus. in color. $b online resource.
336 $a text $b txt $2 rdacontent
337 $a computer $b c $2 rdamedia
338 $a online resource $b cr $2 rdacarrier
347 $a text file $b PDF $2 rda
490 1 $a Nucleic Acids and Molecular Biology, $x 0933-1891 ; $v 33
505 0 $a Assembly of the nuclear pore complex -- Structure of Yeast nuclear pore complexes -- Structure and function of nucleoporins in nuclear transport -- Dynamic structures of the nuclear pore complex and their roles in nucleo-cytoplasmic transport -- Non-canonical roles of nuclear pore proteins -- On the role of the channel nucleoporins in nuclear transport -- Structures of Importins and Exportins -- Navigating the Nuclear Envelope: one or multiple transport mechanisms for integral membrane proteins? -- mRNA export and its dysregulation in disease -- Coarse-grained molecular dynamics of the natively-unfolded domain of the NPC -- On the effects of leukemogenic nucleoporin fusion proteins on nucleocytoplasmic transport and gene expression -- Structure and Function of the Nuclear Pore Complex Revealed by Advanced Fluorescence Microscopy.
520 $a Dysfunction of nuclear-cytoplasmic transport systems has been associated with many human diseases. Thus, understanding of how functional this transport system maintains, or through dysfunction fails to maintain remains the core question in cell biology. In eukaryotic cells, the nuclear envelope (NE) separates the genetic transcription in the nucleus from the translational machinery in the cytoplasm. Thousands of nuclear pore complexes (NPCs) embedded on the NE selectively mediate the bidirectional trafficking of macromolecules such as RNAs and proteins between these two cellular compartments. In this book, the authors integrate recent progress on the structure of NPC and the mechanism of nuclear-cytoplasmic transport system in vitro and in vivo.
650 0 $a Nucleic acids. $3 788506
650 0 $a Microbiology. $3 591510
650 0 $a Evolutionary biology. $3 1199725
650 1 4 $a Nucleic Acid Chemistry. $3 716485
650 2 4 $a Applied Microbiology. $3 673403
650 2 4 $a Eukaryotic Microbiology. $3 676937
650 2 4 $a Evolutionary Biology. $3 668573
700 1 $a Yang, Weidong. $4 edt $4 http://id.loc.gov/vocabulary/relators/edt $3 1206915
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
776 0 8 $i Printed edition: $z 9783319773087
776 0 8 $i Printed edition: $z 9783319773100
776 0 8 $i Printed edition: $z 9783030084257
830 0 $a Nucleic Acids and Molecular Biology, $x 0933-1891 ; $v 31 $3 1274722
856 4 0 $u https://doi.org/10.1007/978-3-319-77309-4
912 $a ZDB-2-SBL
912 $a ZDB-2-SXB
950 $a Biomedical and Life Sciences (SpringerNature-11642)
950 $a Biomedical and Life Sciences (R0) (SpringerNature-43708)