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Haploidentical Transplantation = Con...
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Ciurea, Stefan O.
Haploidentical Transplantation = Concepts & Clinical Application /
Record Type:
Language materials, printed : Monograph/item
Title/Author:
Haploidentical Transplantation/ edited by Stefan O. Ciurea, Rupert Handgretinger.
Reminder of title:
Concepts & Clinical Application /
other author:
Ciurea, Stefan O.
Description:
XI, 337 p. 25 illus., 18 illus. in color.online resource. :
Contained By:
Springer Nature eBook
Subject:
Hematology. -
Online resource:
https://doi.org/10.1007/978-3-319-54310-9
ISBN:
9783319543109
Haploidentical Transplantation = Concepts & Clinical Application /
Haploidentical Transplantation
Concepts & Clinical Application /[electronic resource] :edited by Stefan O. Ciurea, Rupert Handgretinger. - 1st ed. 2018. - XI, 337 p. 25 illus., 18 illus. in color.online resource. - Advances and Controversies in Hematopoietic Transplantation and Cell Therapy,2569-1376. - Advances and Controversies in Hematopoietic Transplantation and Cell Therapy,.
Historical perspective and current trends in haploidentical transplantion -- Part 1: Graft manipulation and methods to control T-cell alloreactivity. -Positive CD34+ cell selection -- Selective allo-depletion: αβ and CD19+ cell T cell depletion -- T cell addback in T- cell depleted haploidentical transplant -- Hematopoietic myeloid growth factor primed bone marrow and peripheral blood hematopoietic progenitor cells -- Photodepletion of allo-reactive T cells -- Post-transplant cyclophosphamide in haploidentical transplant -- Part 2: Ideal graft & donor -- Graft source: Marrow versus peripheral blood with PTCy- Does it matter? -- Anti-HLA antibodies: Assessment and mitigating strategies -- Selection of haploidentical donors: What is the art? -- Myeloablative versus non-myeloablative conditioning regimen- Does it matter and how best to select? -- Part 3: Disease-specific pediatric population -- Nonmalignant diseases in children.- en.-="" part="" 4:="" disease-specific="" adult="" population.-="" non-malignant="" adults.-="" acute="" myelogenous="" leukemia="" lymphomas-="" parameswaran="" hari.-="" chronic="" leukemias="" and="" myeloproliferative="" neoplasms.-="" immunologic="" reconstitution="" after="" haploidentical="" transplantation.-="" prevention="" treatment="" of="" relapse="" transplant.-="" unique="" complications="" limitations="" future="" prospects="" transplantation.
In this book, world-renowned experts in the field express well-reasoned opinions on a range of issues and controversies relating to haploidentical transplantation with the aim of providing practicing hematologists with clinically relevant and readily applicable information. Among the areas covered are graft manipulation and methods to control T-cell alloreactivity, the nature of the ideal graft and donor, haploidentical transplantation in pediatric and adult patients with malignant and nonmalignant diseases, immunologic reconstitution following transplantation, complications, and the prevention and treatment of relapse post transplantation. Attention is drawn to the implications of high-impact clinical trials whenever such trials are available. The readily intelligible text is complemented by numerous helpful tables, algorithms, and figures. The book will provide practical support for hematologists and transplant physicians as they attempt to provide optimal care in this exciting but increasingly complex medical specialty.
ISBN: 9783319543109
Standard No.: 10.1007/978-3-319-54310-9doiSubjects--Topical Terms:
645254
Hematology.
LC Class. No.: RB45
Dewey Class. No.: 616.15
Haploidentical Transplantation = Concepts & Clinical Application /
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Historical perspective and current trends in haploidentical transplantion -- Part 1: Graft manipulation and methods to control T-cell alloreactivity. -Positive CD34+ cell selection -- Selective allo-depletion: αβ and CD19+ cell T cell depletion -- T cell addback in T- cell depleted haploidentical transplant -- Hematopoietic myeloid growth factor primed bone marrow and peripheral blood hematopoietic progenitor cells -- Photodepletion of allo-reactive T cells -- Post-transplant cyclophosphamide in haploidentical transplant -- Part 2: Ideal graft & donor -- Graft source: Marrow versus peripheral blood with PTCy- Does it matter? -- Anti-HLA antibodies: Assessment and mitigating strategies -- Selection of haploidentical donors: What is the art? -- Myeloablative versus non-myeloablative conditioning regimen- Does it matter and how best to select? -- Part 3: Disease-specific pediatric population -- Nonmalignant diseases in children.- en.-="" part="" 4:="" disease-specific="" adult="" population.-="" non-malignant="" adults.-="" acute="" myelogenous="" leukemia="" lymphomas-="" parameswaran="" hari.-="" chronic="" leukemias="" and="" myeloproliferative="" neoplasms.-="" immunologic="" reconstitution="" after="" haploidentical="" transplantation.-="" prevention="" treatment="" of="" relapse="" transplant.-="" unique="" complications="" limitations="" future="" prospects="" transplantation.
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In this book, world-renowned experts in the field express well-reasoned opinions on a range of issues and controversies relating to haploidentical transplantation with the aim of providing practicing hematologists with clinically relevant and readily applicable information. Among the areas covered are graft manipulation and methods to control T-cell alloreactivity, the nature of the ideal graft and donor, haploidentical transplantation in pediatric and adult patients with malignant and nonmalignant diseases, immunologic reconstitution following transplantation, complications, and the prevention and treatment of relapse post transplantation. Attention is drawn to the implications of high-impact clinical trials whenever such trials are available. The readily intelligible text is complemented by numerous helpful tables, algorithms, and figures. The book will provide practical support for hematologists and transplant physicians as they attempt to provide optimal care in this exciting but increasingly complex medical specialty.
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