國立虎尾科技大學 |

Childhood stress, trauma and synapse loss

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Childhood stress, trauma and synapse loss/ by Maxwell R Bennett.
Author:	Bennett, M. R.
Published:	Singapore :Springer Nature Singapore : : 2024.,
Description:	xxi, 191 p. :ill. (some col.), digital ; : 24 cm.;
Contained By:	Springer Nature eBook
Subject:	Child psychology. -
Online resource:	https://doi.org/10.1007/978-981-97-2803-9
ISBN:	9789819728039

Childhood stress, trauma and synapse loss
Bennett, M. R.

Childhood stress, trauma and synapse loss[electronic resource] /by Maxwell R Bennett. - Singapore :Springer Nature Singapore :2024. - xxi, 191 p. :ill. (some col.), digital ;24 cm.

Chapter 1 Vignettes of an Australian childhood -- Chapter 2 Emergence of abnormal psychology following different forms of abuse and neglect -- Chapter 3 Emergence of specific psychopathologies following abuse and neglect -- Chapter 4 Emergence of an abnormal personality -- Chapter 5 The Kraepelin model -- Chapter 6 Kohut and Freud models -- Chapter 7 Hierarchical taxonomy models -- Chapter 8 Brain structures involved in major depressive disorder -- Chapter 9 Synapse pathology in brain structures affected in depression -- Chapter 10 Do molecular interventions (ketamine) re-establish synapses in affected brain structures?.

This book is concerned with the extent to which childhood stress and trauma lead in relative maturity to major depression (MDD) and post-traumatic stress disorder (PTSD) The loss of synapses in the cortex, accompanying childhood maltreatment, is identified as a principal mechanism for developing these disorders. Considerable attention is given to identifying interventions that will restore lost synapses, so ameliorating these mental illnesses. The book describes the emergence of abnormal psychology in youth and adult life following childhood maltreatment. Of considerable immediate concern is the extent to which such maltreatment significantly enhances the tendency to suicide and suicidality. Next, consideration is given as to how personality disorders, such as obsessive-compulsive disorder, the very dangerous borderline personality disorder, and the publicly offensive narcissistic personality disorder, arise from childhood maltreatment. The classification or nosology of mental and personality disorders as well as the principal psychoanalytic approaches available for their treatment are sketched together with recent attempts to use novel constructs that bridge between symptoms (based on patients' behavior and self-descriptions) Recently, new techniques have been developed for brain imaging and non-invasive and localized brain stimulation. These show that nodes of the distributed brain network whose malfunction is closely related to major depressive disorders are likely to differ in their importance from patient to patient. Wonderfully, so-called 'closed-loop' stimulation techniques are now available for automatically adjusting the activity of individual nodes in individual patients, relieving them of their major depression. The results of our research, and that of others using magnetic resonance imaging of mature patients that have been maltreated as children, have been to identify the nodes that have lost gray matter. We have shown that this is likely due to the loss of synapses in these nodes. Finally, the central question of how synapses may be restored in these nodes to ameliorate major depressive disorders, post-traumatic stress disorder, and suicidality is considered, emphasizing the recent revolutionary discovery that the psychedelic ketamine restores synapses and has a therapeutic effect on mental health.

ISBN: 9789819728039

Standard No.: 10.1007/978-981-97-2803-9doiSubjects--Topical Terms:

561946
Child psychology.

LC Class. No.: BF721

Dewey Class. No.: 155.4

Childhood stress, trauma and synapse loss
LDR:03959nam a2200325 a 4500 001 1133556
003 DE-He213
005 20240713130849.0
006 m d
007 cr nn 008maaau
008 241213s2024 si s 0 eng d
020 $a 9789819728039 $q (electronic bk.)
020 $a 9789819728022 $q (paper)
024 7 $a 10.1007/978-981-97-2803-9 $2 doi
035 $a 978-981-97-2803-9
040 $a GP $c GP
041 0 $a eng
050 4 $a BF721
072 7 $a PSAN $2 bicssc
072 7 $a SCI089000 $2 bisacsh
072 7 $a PSAN $2 thema
082 0 4 $a 155.4 $2 23
090 $a BF721 $b .B472 2024
100 1 $a Bennett, M. R. $3 573715
245 1 0 $a Childhood stress, trauma and synapse loss $h [electronic resource] / $c by Maxwell R Bennett.
260 $a Singapore : $c 2024. $b Springer Nature Singapore : $b Imprint: Springer,
300 $a xxi, 191 p. : $b ill. (some col.), digital ; $c 24 cm.
505 0 $a Chapter 1 Vignettes of an Australian childhood -- Chapter 2 Emergence of abnormal psychology following different forms of abuse and neglect -- Chapter 3 Emergence of specific psychopathologies following abuse and neglect -- Chapter 4 Emergence of an abnormal personality -- Chapter 5 The Kraepelin model -- Chapter 6 Kohut and Freud models -- Chapter 7 Hierarchical taxonomy models -- Chapter 8 Brain structures involved in major depressive disorder -- Chapter 9 Synapse pathology in brain structures affected in depression -- Chapter 10 Do molecular interventions (ketamine) re-establish synapses in affected brain structures?.
520 $a This book is concerned with the extent to which childhood stress and trauma lead in relative maturity to major depression (MDD) and post-traumatic stress disorder (PTSD) The loss of synapses in the cortex, accompanying childhood maltreatment, is identified as a principal mechanism for developing these disorders. Considerable attention is given to identifying interventions that will restore lost synapses, so ameliorating these mental illnesses. The book describes the emergence of abnormal psychology in youth and adult life following childhood maltreatment. Of considerable immediate concern is the extent to which such maltreatment significantly enhances the tendency to suicide and suicidality. Next, consideration is given as to how personality disorders, such as obsessive-compulsive disorder, the very dangerous borderline personality disorder, and the publicly offensive narcissistic personality disorder, arise from childhood maltreatment. The classification or nosology of mental and personality disorders as well as the principal psychoanalytic approaches available for their treatment are sketched together with recent attempts to use novel constructs that bridge between symptoms (based on patients' behavior and self-descriptions) Recently, new techniques have been developed for brain imaging and non-invasive and localized brain stimulation. These show that nodes of the distributed brain network whose malfunction is closely related to major depressive disorders are likely to differ in their importance from patient to patient. Wonderfully, so-called 'closed-loop' stimulation techniques are now available for automatically adjusting the activity of individual nodes in individual patients, relieving them of their major depression. The results of our research, and that of others using magnetic resonance imaging of mature patients that have been maltreated as children, have been to identify the nodes that have lost gray matter. We have shown that this is likely due to the loss of synapses in these nodes. Finally, the central question of how synapses may be restored in these nodes to ameliorate major depressive disorders, post-traumatic stress disorder, and suicidality is considered, emphasizing the recent revolutionary discovery that the psychedelic ketamine restores synapses and has a therapeutic effect on mental health.
650 0 $a Child psychology. $3 561946
650 0 $a Child psychotherapy. $3 555170
650 0 $a Stress in children. $3 1114342
650 1 4 $a Neuroscience. $3 569964
650 2 4 $a Neurological Disorders. $3 1388151
650 2 4 $a Neurophysiology. $3 582158
650 2 4 $a Cognitive Neuroscience. $3 1237796
710 2 $a SpringerLink (Online service) $3 593884
773 0 $t Springer Nature eBook
856 4 0 $u https://doi.org/10.1007/978-981-97-2803-9
950 $a Biomedical and Life Sciences (SpringerNature-11642)